* Equal Contribution, # Corresponding Author(s)

2024

26. R. S. Wertzman, W. Yost, B. I. Herrmann, C. M. Bourne, D. Sorobetea, C. K. Go, B. S. Saller, O. Groß, P. Scott, A. Rongvaux, C. Y. Taabazuing, I. E. Brodsky#. “Distinct sequential death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling” (2024) Science Advances, (2024) 10: eadl3629

25. P. M. Exconde*, C. M. Bourne*, M. Kulkarni, B. M. Discher, C. Y. Taabazuing#, “Inflammatory caspase substrate specificities” (2024) mBio 15:7 e02975-23 (Invited Review)

24. C. M. Bourne, C. Y. Taabazuing#, “Harnessing pyroptosis for cancer immunotherapy” (2024) Cells 13(4): 346 (Invited Review)

23. D. C. Akuma*, K. A. Wodzanowski*, R. S. Wertman*, P. M. Exconde, V. R. Vázquez-Marrero, C. E. Odunze, D. Grubaugh, S. Shin#, C. Y. Taabazuing#, I. E. Brodsky#. “Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS” (2024) eLife 13: e83725

2023

22. P. M. Exconde, C. Hernandez-Chavez, C. M. Bourne, R. M. Richards, M. B. Bray, J. L. Lopez, T. Srivastava, M. S. Egan, J. Zhang, S. Shin, B. M. Discher, and C. Y. Taabazuing#. “The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases” (2023) Cell Reports 42: 113581

21.  A. Mays, A. Byars-Winston, A. Hinton Jr., A. G. Marshall, A. Kirabo, A. August, B. J. Marlin, B. Riggs, B. Tolbert, C. Wanjalla, C. Womack, C. S. Evans, C. Barnes, C. Starbird, C. Williams, C. Reynolds, C. Y. Taabazuing, C. E. Cameron, D. D. Murray, D. Applewhite, D. J. Morton, D. Lee, D. W. Williams, D. Lynch, D. Brady, E. Lynch, F. U. N. Rutaganira, G. M. Silva, H. Shuler, I. A. Saboor, J. Davis, K. Dzirasa, L. Hammonds-Odie, L. Reyes, M. T. Sweetwyne, M. R. McReynolds, M. D.L. Johnson, N. A. Smith, N. Pittman, O. A. Ajijola, Q. Smith, R. A.S. Robinson, S. C. Lewis, S. A. Murray, S. Black, S. E. Neal, S. Andrisse, S, Townsend, S. M. Damo, T. N. Griffith, W. M. Lambert, W. M. Clemons Jr. “Juneteenth in STEMM and the barriers to equitable science” (2023) Cell 186(12):2510-2517

20.  E. Ransey, S. Brookens, H. K. Beasley, A. Marshall, B. J. Marlin, P. Rodriguez-Aliaga, C. A. Headley, C. Wanjalla, A. D. Vazquez, S. Murray, S. Damo, C. Y. Taabazuing# and A. Hinton Jr.# “A practical guide to graduate school interviewing for historically excluded individuals” (2023) American Journal of Physiology-Heart and Circulatory Physiology 324(6)H786-H790

19.  P. M. Exconde, C. Hernandez-Chavez, M. B. Bray, J. L. Lopez, T. Srivastava, M. S. Egan, J. Zhang, S. Shin, B. M. Discher, and C. Y. Taabazuing# “The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases” (2023) bioRxiv, p. 2023.02.16.528859

2022

18. D. C. Akuma, D. Grubaugh, C. E. Odunze, S. Shin, C. Y. Taabazuing, I. E. Brodsky. “Noncanonical inflammasome assembly requires caspase-11 catalytic activity and intra-molecular autoprocessing” (2022) bioRxiv, p. 2022.09.21.508824

17. J. C. Hsiao, A. R. Neugroschl, A. J. Chui, C. Y. Taabazuing, A. R. Griswold, Q. Wang, H. Huang, E. L. Orth, D. P. Ball, G. Hiotis, & D. A. Bachovchin. “A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome” (2022) Journal of Biological Chemistry 298(7): 102032

C. Y. Taabazuing “Introducing new group leaders: Cornelius Taabazuing” (2022) Molecular Cell 82: 1079—1080

2020

16.  A. J. Chui, A. R. Griswold, C. Y. Taabazuing, E. L. Orth, K. Gai, S. D. Rao, D. P. Ball, & D. A. Bachovchin. “Activation of the CARD8 inflammasome requires a disordered region” (2020) Cell Reports 33(2): 108264

15.  C. Y. Taabazuing, A. R. Griswold, D.A Bachovchin, “The NLRP1 and CARD8 inflammasomes” (2020) Immunological Reviews 297: 1 – 13 (Invited Review)

14.  D. P. Ball,* C. Y. Taabazuing,* A. R. Griswold, E. L. Orth, S. D. Rao, I. B. Kotliar, L. E. Vostal D. C. Johnson, D.A Bachovchin, “Caspase-1 interdomain linker cleavage is required for pyroptosis” (2020) Life Science Alliance 3(3): e202000664

2019

13.  A. R. Griswold, D. P. Ball, A. Bhattacharjee, A. J. Chui, S. D. Rao, C. Y. Taabazuing, D. A. Bachovchin. “DPP9’s enzymatic activity and not its binding to CARD8 inhibits inflammasome activation” (2019) ACS Chemical Biology 14: 2424−2429

12.  A. J. Chui,* M. C. Okondo,* S. D. Rao,* K. Gai, A. R. Griswold, D. C. Johnson, D. P. Ball, C. Y. Taabazuing, E. L. Orth, B. A. Vittimberga, D. A. Bachovchin. “N-terminal degradation activates the NLRP1B inflammasome” (2019) Science 364(6435): 82 – 85

2018

11.  D. C. Johnson,* C. Y. Taabazuing,* M. C. Okondo, A. J. Chui, S. D. Rao, F.C. Brown, C. Reed, E. Peguero, E. de Stanchina, A. Kentsis, D.A Bachovchin, “DPP8/9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia” (2018) Nature Medicine 24(8): 1151 – 1156

10.  M. C. Okondo,* S. D. Rao,* C. Y. Taabazuing,* A. J. Chui, S. E. Poplawski, D. C. Johnson,  D. A. Bachovchin. “Inhibition of DPP8/9 activates the Nlrp1b inflammasome” (2018) Cell Chemical Biology 25: 262-267

2017

9. C. Y. Taabazuing, M. C. Okondo, and D. A. Bachovchin. “Pyroptosis and apoptosis pathways engage in bidirectional crosstalk in monocytes and macrophages” (2017) Cell Chemical Biology 24: 507-514.

8. J. A. Hangasky, C. Y. Taabazuing, C.B. Martin, S. Eron, S. C. Garman, and M. J. Knapp. “The facial triad in the αKG oxygenase Factor Inhibiting HIF (FIH): a role for sterics in linking substrate binding to O2 activation.” (2017) Journal of Inorganic Biochemistry 166: 26-33.

2016

7. C. Y. Taabazuing, J. T. Fermann, S. C. Garman, M. J. Knapp. “Substrate promotes productive gas binding in the αKG-dependent oxygenase FIH” (2016) Biochemistry 55(2): 277-286

2015

6. S. Pektas, C. Y. Taabazuing, M. J. Knapp. “Increased turnover under limiting [O2] by the Thr387 → Ala mutant of the HIF-prolyl hydroxylase PHD2” (2015) Biochemistry 54(18): 2851-2857

2014

5. C. Y. Taabazuing, J. A. Hangasky, M. J. Knapp. “Oxygen sensing strategies in mammals and bacteria” (2014) Journal of Inorganic Biochemistry 133: 63-72 (Special Issue: “Gas and Redox Sensors”) cover artwork

2013

4. J. A. Hangasky, C. Y. Taabazuing, M. A. Valliere, and M. J. Knapp. “Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the αKG-dependent oxygenases.”  (2013) Metallomics 5(4):287-301 (Themed Issue: “Microbial Metallomics”)

2012

3. J. S. Pfingsten, K. J. Goodrich, C. Y. Taabazuing, F. Ouenzar, P. Chartrand and T.R. Cech. "Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model." (2012) Cell 148(5):922-932.

2. S. C. Flagg C. B. Martin, C. Y. Taabazuing, B. E. Holmes and M. J. Knapp. "Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH)." (2012) Journal of Inorganic Biochemistry 113(0): 25-30.

2011

1.  E. Saban, Y.-H. Chen, J. A. Hangasky, C. Y. Taabazuing, B. E. Holmes and M. J. Knapp. "The second coordination sphere of FIH controls hydroxylation." (2011) Biochemistry 50(21): 4733-4740.